Could erlotinib treatment lead to acute cardiovascular events in patients with lung adenocarcinoma after chemotherapy failure?
Kus T, Aktas G, Sevinc A, Kalender ME, Camci C
Onco Targets Ther. 2015 Jun 5;8:1341-3. doi: 10.2147/OTT.S84480. eCollection 2015.
CARDIONCOLOGY.ORG ABSTRACT:
Unlike other targeted tyrosine kinase inhibitors, data on erlotinib do not indicate that is is associated with increased acute cardiovascular event (ACE) risk.
Despite not being a cardiotoxic drug itself, preclinical studies suggest an aggregate effect of erlotinib on ACE, This article presents two non-small-cell lung cancer cases that developed ACE under erlotinib treatment.
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fonte foto: https://en.wikipedia.org/wiki/Erlotinib