Importance of Immunotherapy in the Treatment of Solid Tumors
- presentation held at the A.R.C.A.cardio-oncology workshop ABCDEFG - Florence 02-2020-
Paolo Tralongo
(Thanks to Dr. Paolo Tralongo for sharing this presentation through cardioncology.org)
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PRESENTATION TOPICS
(presentation content mostly in English language)
- How many urvivors: 1993 vs 2016
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Immune system and cancer
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Three Main Approaches to Cancer Immunotherapy
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Active immunization to enhance anti-tumor reactions (cancer vaccines)
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Passively transfer activated immune cells with anti-tumor activity (adoptive cell transfer >> CAR T-cells)
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Non-specific stimulation of immune reactions
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Stimulate effector cells
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IL-2 (melanoma, renal cell)
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Inhibit regulatory factors
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Anti-CTLA4
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Anti-PD1 / Anti-PDL1
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New Frontier: Immune Checkpoint Inhibitor
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