Updates in Anthracycline-Mediated Cardiotoxicity
Nebigil CG, Désaubry L.
Front Pharmacol. 2018 Nov 12;9:1262. doi: 10.3389/fphar.2018.01262. eCollection 2018.
CARDIONCOLOGY.ORG ABSTRACT:
Anthracyclines are associated with major cardiotoxicity that can ultimately culminate in congestive heart failure when used in cancer therapy.
This review focuses on the key progenitor cells and cardiac cells (cardiomyocytes, fibroblasts, and vascular cells), focusing on the signaling pathways involved in cellular damage, and the clinical biomarkers in anthracycline- mediated cardiotoxicity.
© All Rights Reserved